Inhouse product
The following data describe the MSTITR41VSWISS volumetric Karl Fischer titrator. This is the standard entry model in MASTER SCIENCE‘s Karl Fischer titration line, designed for routine quality control applications where advanced compliance features are not required. All values are measured under the manufacturer’s standard test conditions.
Model number: MSTITR41VSWISS
Instrument type: Volumetric Karl Fischer titrator (standard entry model)
Titration method: Volumetric Karl Fischer titration
Water content range: 0.1 to 250.0 mg
Water resolution: 1 μg
Water units: μg, mg, %, ppm, μg/mL, mg/L (selectable)
Water repeatability: ≤0.5%
mV range: 0 to 2000 mV
mV resolution: 1 mV
Polarization current accuracy: ±3%
Polarization current fluctuation: ±2.5% per 30 minutes
Supported methods: Auto Titration Method, KF Titer Determination Method, Oven Titration Method, Oven Blank Titration Method
Display: 7.0‑inch high‑contrast colour LCD touchscreen
Solvent manager: Basic function – solvent feeding and waste draining only; no automatic mixing or burette cleaning
Sample types: Liquids, solids, and gases (with oven sampling method)
Data management: Basic single password lock; simplified GMP records without full lifecycle reagent/sensor management
Data storage: Up to 200 titration data sets (basic GLP‑compliant)
Communication: RS‑232 (print, configurable format), USB (PC software), USB port (U disk data export in CSV format only)
External device support: Oven sampling only; no balance or barcode scanner interface
Drift correction: Basic drift correction only; no coefficient correction function
Power supply: AC 100‑240V, 47‑63Hz
Dimensions: 240 × 370 × 270 mm
Net weight: Approximately 4 kg
Included accessories: Solvent manager (basic), 10mL burette, volumetric vessel, measuring electrode
The specifications above translate into practical improvements for everyday moisture testing. Each point below connects a feature to a measurable outcome.
Wide water measurement range for diverse samples – The 0.1 to 250.0 mg water range covers medium‑to‑high moisture content samples above 0.1mg. A chemical raw materials laboratory measuring moisture in solvents, oils, and bulk powders uses a single instrument across multiple product lines.
High resolution for confident results – The 1μg resolution detects water at the parts‑per‑million level. A QC technician measuring moisture in petrochemicals sees clear differentiation between acceptable and rejectable batches. Batch release decisions become more confident.
Oven sampling method extends application range – Gases, solids, and viscous liquids that do not dissolve readily in the titration vessel are measured using the oven method. A researcher analysing moisture in polymer pellets or insulating oils inserts the sample into the oven, and the evaporated water is carried into the titration cell. No complicated sample preparation, no solubility issues.
Basic GLP data storage for routine audits – The instrument stores up to 200 titration data sets with simplified GMP records. A quality control laboratory preparing for an internal audit exports the complete titration history in CSV format via the USB port.
Adjustable drift compensation ensures accuracy – Basic drift correction compensates for background moisture from the atmosphere and reagents. A laboratory measuring moisture in hygroscopic samples runs the drift compensation before each titration. The result reflects the sample moisture, not the ambient humidity.
Pain point: Inconsistent results due to manual reagent handling.
Manual filling and draining of Karl Fischer reagents introduces air bubbles and volume errors. The MASTER SCIENCE MSTITR41VSWISS volumetric Karl Fischer titrator (a standard entry model with basic solvent feeding and waste draining) automates the essential reagent handling steps. A laboratory running 30 titrations per day sees consistent precision from the first to the last sample. Repeatability stays ≤0.5%.
Pain point: Difficulty measuring moisture in solids and gases.
Standard Karl Fischer titrators require the sample to dissolve in the titration solvent. The same MASTER SCIENCE MSTITR41VSWISS volumetric Karl Fischer titrator (supporting oven sampling for solids, gases, and viscous liquids) evaporates the moisture from the sample and carries it into the titration cell. A petrochemical laboratory analysing insulating oil, a polymer plant testing resin pellets, and a gas supplier measuring moisture in compressed air all use the same instrument.
Pain point: Limited budget for advanced compliance features.
Not every laboratory needs full GMP lifecycle management or multi‑level user permissions. The MASTER SCIENCE MSTITR41VSWISS volumetric Karl Fischer titrator (a cost‑effective model with basic GLP data storage for up to 200 data sets) provides essential data traceability without the expense of advanced compliance features. A chemical raw materials QC laboratory meets internal audit requirements without over‑investing.
Pain point: Slow, manual data entry into laboratory information systems.
A technician copies results from the instrument display to a paper logbook, then enters them into the LIMS. The MASTER SCIENCE MSTITR41VSWISS volumetric Karl Fischer titrator (with USB port for CSV data export) transfers results directly. A USB drive inserted into the port copies all new titrations in CSV format. The file imports into the LIMS in seconds. No transcription, no transposition errors.
Pain point: Exposure to toxic Karl Fischer reagents.
Pyridine‑based reagents are neurotoxic. Methanol is flammable and toxic. The MASTER SCIENCE MSTITR41VSWISS volumetric Karl Fischer titrator (with basic solvent manager for feeding and draining) keeps reagents in sealed containers. The operator does not pour or transfer reagents manually. Staff exposure is reduced significantly compared to fully manual systems.
Chemical raw materials quality control – Routine QC testing of incoming and outgoing chemical raw materials without strict audit rules. The instrument handles medium‑to‑high moisture content samples above 0.1mg. The basic GLP data storage supports internal quality records.
Petrochemical and lubricant laboratories – Determine water content in transformer oils, hydraulic fluids, lubricating oils, and fuels. The oven sampling method handles viscous and non‑dissolving samples. The 0.1‑250mg range covers typical moisture levels in petroleum products.
Small to medium manufacturing facilities – Low daily test volume and limited budget. The instrument provides reliable moisture analysis without the cost of advanced compliance features. The basic solvent manager reduces manual reagent handling.
Academic and research laboratories – Teach Karl Fischer titration principles to students. The touchscreen interface and basic automation reduce student errors. The instrument supports method development for novel sample types with oven sampling.
Food and beverage testing laboratories – Measure moisture in dried foods, spices, and powdered milk. The volumetric method handles the higher moisture levels typical of food products. The selectable units (%, ppm, mg/L) match reporting requirements.
Installation – The instrument stands on a bench (240 × 370 × 270 mm) weighing 4 kg. The solvent manager and reagent bottles are placed beside or behind the instrument. The titration vessel sits on the magnetic stirrer base.
Setting up a method – The 7‑inch touchscreen displays the method editor. The operator selects Auto Titration, KF Titer Determination, Oven Titration, or Oven Blank. The operator enters the expected water range, selects the basic drift compensation mode, and sets the endpoint criteria. The method saves under a user‑selected name.
Running a titration – The operator weighs the sample and enters the weight. The instrument fills the burette, adjusts the drift, and starts the titration. The screen displays the titration curve in real time. At the endpoint, the instrument calculates the water content and displays the result in the selected unit.
Oven method – The operator places the sample in a sealed vial, inserts the vial into the oven, and connects the oven to the titration cell. The oven heats the sample, and a carrier gas (dry air or nitrogen) carries the evaporated water into the titration cell. The instrument titrates the water and reports the result.
Data export – Insert a USB drive into the USB port. Navigate to the data management menu. Select the data sets to export. The instrument writes a CSV file to the USB drive. Connect the instrument to a PC via USB for real‑time data transfer using the supplied PC software.
The MSTITR41VSWISS uses open reagents. Merck‘s Aquastar® range is the recommended choice for reliable and accurate Karl Fischer titration results.
A Reagent (Solvent) – Merck Aquastar® Solvent for volumetric Karl Fischer titration with two‑component reagents. Product number: 1.88015 (Catalogue No. 188015). This solvent is used as the titration medium in the vessel.
B Reagent (Titrant) – Merck Aquastar® Titrant 5 for volumetric Karl Fischer titration with two‑component reagents, 1 ml ≙ ca. 5 mg H₂O. Product number: 1.88010 (Catalogue No. 188010). This titrant is dispensed from the burette to react with water in the sample.
Both reagents are available through Merck, Sigma‑Aldrich, and authorised distributors. These reagents are highly flammable and toxic; handle in accordance with the safety data sheet (SDS). The solvent manager‘s basic feeding and draining functions reduce manual exposure during operation.
Reagent replacement – The instrument alerts the user when titrant or solvent levels are low. The solvent manager drains the waste and feeds fresh reagents automatically. The operator changes reagent bottles when empty. No manual pouring.
Burette cleaning – The MSTITR41VSWISS solvent manager does not include automatic burette cleaning. The operator performs manual cleaning periodically using fresh titrant or a suitable solvent. A clean burette ensures accurate titrant delivery.
Electrode maintenance – The measuring electrode is cleaned with a suitable solvent after each use. The user manual provides detailed cleaning procedures.
Calibration – The instrument is factory‑calibrated. The KF Titer Determination Method checks the titrant concentration against a certified water standard. The instrument calculates the titer and adjusts subsequent titrations accordingly. Annual recalibration is recommended for regulated applications.
The MSTITR41VSWISS ships as a complete kit including:
MSTITR41VSWISS main unit with 7‑inch touchscreen
Solvent manager (basic: solvent feeding and waste draining)
10mL burette
Volumetric titration vessel
Measuring electrode
Magnetic stirrer (integrated)
Power cord (AC 100‑240V, 47‑63Hz)
RS‑232 cable
USB cable
PC software (on CD or download link)
User manual with calibration certificate
Quick start guide
Reagents (order separately, locally):
A Reagent (Solvent): Merck 1.88015 (Aquastar® Solvent)
B Reagent (Titrant): Merck 1.88010 (Aquastar® Titrant 5)
The customer should specify the following when ordering:
Model number (MSTITR41VSWISS)
Voltage (AC 100‑240V, 47‑63Hz – universal)
Optional accessories available:
Oven sampling accessory (for solids and gases)
Additional 10mL burettes
Spare measuring electrodes
Calibration verification standards
Thermal printer (for printed reports)
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