In the fast-paced world of molecular biology and genomics, the demand for high-quality synthetic DNA is constant. Researchers require a reliable, efficient, and scalable solution to produce primers, probes, and genes for their critical experiments. The DNA Synthesizer is engineered to meet these exacting standards, providing a robust platform for high-throughput oligonucleotide production. This system is designed to streamline your workflow, from basic research to complex diagnostic development, ensuring you achieve consistent and accurate results every time. Let’s explore how this advanced DNA Synthesizer can elevate your laboratory’s capabilities.

Technical Specifications

This advanced DNA Synthesizer is built for precision and scalability. Each component is selected to ensure optimal performance and reproducible synthesis.

• Synthesis Scale: 0.2 µmol, 0.5 µmol, 1.0 µmol (and other custom scales available)
• Number of Columns: 192 independent synthesis columns (expandable to 384)
• Synthesis Cycle Time: Approx. 6.5 minutes for a 20-mer at 1.0 µmol scale
• Coupling Efficiency: ≥ 99.5% per step
• Trityl Monitoring: Real-time, inline UV-Vis monitoring for quality control
• Reagent Positions: 12 amidite ports, 10 reagent ports, 4 auxiliary ports
• Delivery System: High-precision micro-solenoid valves and positive displacement pumps
• Waste Management: Separate waste lines for hazardous and non-hazardous reagents
• Operating System: Integrated touchscreen PC with intuitive synthesis software
• Data Management: LIMS-compatible with network connectivity for remote monitoring
• Power Requirements: 100-240 VAC, 50/60 Hz, 500W
• Dimensions (W x D x H): 65 cm x 60 cm x 45 cm
• Weight: 55 kg
• Model/Part Number: OM-DNAS-192

Standard Accessories Included:

• 192-column synthesis reaction plate (1 set)
• Reagent bottles and caps (full set)
• Amidite vials and septa (pack of 12)
• Waste container kit
• Installation and operation manual
• Tool kit for routine maintenance

Items Excluded:

• Reagents (amidites, activators, oxidizers, deblocking solutions)
• Synthesis columns (consumable)
• External computer or monitor (optional)
• Uninterruptible Power Supply (UPS)
• Argon or Nitrogen gas supply and regulator

Pre-installation Requirement:

• A clean, dust-free laboratory environment with adequate ventilation.
• A stable benchtop or floor space that meets the system’s dimensions and weight requirements.
• Access to a standard electrical outlet (100-240 VAC).
• An inert gas supply (Argon or Nitrogen) with a two-stage regulator.
• Network connection for data management and remote support.

Key Benefits: Precision, Efficiency, and Reliability

Struggling with inconsistent yields or time-consuming manual synthesis? The DNA Synthesizer directly addresses these common laboratory pain points. By integrating advanced fluidics with real-time monitoring, this system ensures your lab operates at peak performance.

Unmatched Precision and Accuracy
The core of this DNA Synthesizer is its high-precision delivery system. This technology guarantees accurate reagent dispensing, leading to a coupling efficiency of ≥ 99.5%. This precision directly translates to higher yields of full-length oligonucleotides, reducing the need for costly and time-consuming purification steps. For researchers, this means greater confidence in downstream applications like qPCR, NGS, and gene assembly. You can learn more about the importance of synthesis quality from resources like the Oligomaker application notes.

Enhanced Lab Efficiency and Throughput
The 192-column format of this DNA Synthesizer allows you to produce hundreds of oligos in a single run. The automated software schedules synthesis, monitors reagent levels, and provides real-time status updates, freeing up valuable researcher time. This high-throughput capability accelerates projects, from screening hundreds of primers to building complex gene libraries, making it an indispensable tool for any modern genomics lab. To see how this equipment integrates into a complete workflow, you can explore the solutions offered by OS4U.

Built for Reliability and Low Maintenance
Designed with robust components and a user-friendly interface, this DNA Synthesizer minimizes downtime. The system’s self-diagnostic routines and easy-to-access maintenance points ensure that your lab can rely on it day in and day out. This reliability is crucial for core facilities and commercial labs where operational continuity is paramount. The DNA Synthesizer is more than a piece of equipment; it’s a dependable partner in your research.

Warranty & Support

We are committed to your success. Every DNA Synthesizer comes with a 1-year manufacturer’s warranty covering parts and labor. Our support extends beyond the sale with technical support, installation assistance, and operational training. Replacement parts and consumables are available throughout the product’s service life to ensure uninterrupted operation.

Call to Action: Request a Quotation or Technical Datasheet

Ready to enhance your oligonucleotide synthesis capabilities? Contact us for more information, customized configurations, and solutions tailored to your specific requirements. Our team is ready to help you find the perfect DNA Synthesizer for your lab. Request a quotation or a detailed technical datasheet today.