Benchtop Microbial Bioreactor – Glass Vessel 0.2-50L – Siemens PLC Controller

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The following specifications describe a laboratory‑scale fermenter for microbial culture. Model MSINOBIO‑JGSWISS is the base configuration. All volumes and options can be customised to match your research needs.

Technical Specifications

  • Model number: MSINOBIO‑JGSWISS

  • Product name: Benchtop Microbial Bioreactor (basic benchtop bioreactor)

  • Primary application: microbial culture (bacteria, yeast, fungi)

  • Volume range: 0.2 L to 50 L, freely customisable

  • Load rate: 30%–70%

  • Vessel material: borosilicate glass

  • Vessel design: round bottom for precise processing and better mixing

  • Vessel options: single‑wall glass with electric heating blanket, or double‑wall with jacketed water circulation

  • Stirring system: customised; mechanical stirring (standard) or magnetic stirring (optional); different stirring paddle types can be replaced

  • Gassing: standard with one air intake; optional multiple air intakes

  • Gas control: standard rotor flowmeter (manual); optional mass flowmeter (automatic)

  • Sterilisation: in autoclave

  • Controller: 10‑inch touch screen, easy to understand and use; combines measurement and control hardware for excellent process control

  • Peristaltic pumps: standard with 4 pumps; functions of each pump can be switched; external pumps can be configured

  • External chiller: optional; no need to search for a suitable cooling water source

  • Control system: Siemens PLC (mature, stable, universal)

  • Control functions: real‑time display, data recording, data analysis, output printing, password management, abnormal analysis, over‑limit alarm

  • Data interface: USB port for direct data copying

  • Running modes:

    • Manual control: open valve or set percentage of valve opening

    • Automatic control: select continuous or PID control

    • Sequence control: all parameters can be pre‑set with at least 10 control sections

    • Automatic segmentation remote control: PC control

  • Related control: rotational speed & dissolved oxygen (DO); gassing & DO; feeding & pH

  • Basic control parameters: temperature, rotational speed, pH, DO, antifoam, feeds

  • Stirring mode: mechanical (standard) or magnetic (optional)

  • Power supply: not specified on page; contact supplier for details

  • Dimensions: not specified on page; contact supplier for details

  • Weight: not specified on page; contact supplier for details

Benefits for microbial fermentation laboratories

The features listed above translate directly into practical gains for researchers. Each point below connects a specification to a measurable improvement.

Flexible vessel sizing for different microbial strains – The volume is freely customisable from 0.2 L to 50 L. A small vessel (0.2–2 L) works for high‑throughput screening of bacterial clones. A larger vessel (10–50 L) handles scale‑up studies for yeast fermentation. You buy one system and change vessel sizes as your projects grow.

Round bottom geometry improves mixing and oxygen transfer – Flat‑bottom vessels create dead zones where cells settle and oxygen gradients form. The round bottom design ensures more precise processing and better mixing. This directly translates to higher viable cell densities and more reproducible fermentation outcomes.

Siemens PLC eliminates control system failures – Many low‑cost bioreactors use unreliable proprietary controllers that crash mid‑run. The Siemens PLC is a mature, stable, universal industrial controller. It runs for weeks without rebooting, and data logging continues uninterrupted. Your experiment finishes on time, not after a controller reset.

Four peristaltic pumps handle complex feeding strategies – Fed‑batch fermentations require multiple additions: acid, base, antifoam, and nutrient feed. The MSINOBIO‑JGSWISS benchtop microbial bioreactor comes standard with four peristaltic pumps. Each pump function can be switched, and external pumps can be added. You can run DO‑stat feeding, pH‑stat feeding, and pulse feeding without buying extra hardware.

Sequence control with 10+ segments automates entire runs – Manual adjustment of temperature, pH, and DO across different growth phases is tedious and prone to error. Sequence control allows you to pre‑set at least 10 control sections. The MSINOBIO‑JGSWISS benchtop microbial bioreactor runs an 8‑hour induction protocol or a 48‑hour fed‑batch profile completely unattended. Walk away at 6 PM and collect clean data at 9 AM.

External chiller option removes cooling water dependency – Many laboratories lack a dedicated chilled water supply. The optional external chiller provides closed‑loop cooling. You do not need to find a suitable cooling water source for your bioreactor. Set up the unit on any bench with a power outlet and start fermenting.

Common pain points in microbial fermentation – and how this bioreactor solves them

Pain point: Inconsistent dissolved oxygen (DO) control across replicates.
Poor DO control leads to variable metabolite production. The MSINOBIO‑JGSWISS benchtop microbial bioreactor (a basic but fully featured glass fermenter) includes related control functions: rotational speed linked to DO, and gassing linked to DO. When DO drops, the system automatically increases agitation or airflow. No manual intervention required. Batch‑to‑batch consistency improves immediately.

Pain point: Lost data when power flickers or the controller freezes.
A power interruption of even one second can destroy a 24‑hour fermentation. The same MSINOBIO‑JGSWISS benchtop microbial bioreactor (with Siemens PLC data protection) includes real‑time data recording, password management, and abnormal analysis. The system logs every parameter every few seconds. If a failure occurs, you have a complete record up to the moment of interruption. You restart from known conditions, not from guesswork.

Pain point: Difficulty scaling up from small shake flasks to bioreactors.
Shake flask conditions rarely translate directly to stirred tank reactors. The MSINOBIO‑JGSWISS benchtop microbial bioreactor (a scalable fermenter with mechanical stirring) allows you to match tip speed, power input, and aeration rates to production‑scale units. The mechanical stirring system (standard) with replaceable paddle types mimics larger fermenter hydrodynamics. Scale‑up becomes a calculation exercise rather than a series of failed runs.

Pain point: pH drift due to inadequate control algorithms.
Some bioreactors use simple on‑off pH control, causing overshoot and oscillation. The MSINOBIO‑JGSWISS benchtop microbial bioreactor (equipped with PID automatic control) offers continuous PID control. The system anticipates drift and adjusts pump speed before the pH moves outside the setpoint range. Cultures stay at the optimal pH for longer periods, increasing yield.

Pain point: No way to prove data integrity for regulatory submissions.
Quality control and GMP‑like environments require audit trails. The MSINOBIO‑JGSWISS benchtop microbial bioreactor (a fully documented fermentation workstation) includes password management, abnormal analysis, and over‑limit alarms. All events are timestamped. Data can be copied directly via the USB interface. You can provide regulators with complete, uneditable run records.

Which laboratories benefit most from this bioreactor

Academic microbiology labs screening bacterial mutants will use the manual and automatic control modes. Bioprocess development groups optimising yeast fermentation parameters will use sequence control with 10+ segments. Pharmaceutical QC labs performing release testing for probiotic products will rely on the real‑time data recording and over‑limit alarms. Food science researchers culturing lactic acid bacteria for dairy applications will use the four peristaltic pumps for precise pH and nutrient control. Any laboratory that currently uses shake flasks or uncontrolled water baths for microbial culture will see immediate improvements in reproducibility.

Vessel and accessory options

The borosilicate glass vessel is autoclavable, so you can sterilise it in your existing autoclave. No separate steam generator is needed. The single‑wall electric heating blanket option is simpler and less expensive, suitable for most bacterial cultures. The double‑wall jacketed water circulation option provides faster heating and cooling, useful for temperature‑sensitive yeast strains or rapid shift experiments.

The optional mass flowmeter (automatic gas control) replaces the standard rotor flowmeter. Mass flowmeters are recommended for precise aeration studies, oxygen uptake rate calculations, and any experiment where gas flow rate must be recorded digitally.

The optional external chiller is recommended for laboratories without central cooling water or for experiments requiring temperatures below ambient (e.g., cold shock studies).

Physical configuration and daily operation

The 10‑inch touch screen displays all parameters simultaneously. An operator can see temperature, pH, DO, rotational speed, foam level, and pump status on one screen. The USB port is located on the front panel or side panel for easy access. Data is copied to a standard USB flash drive in comma‑separated format, readable by Excel, Python, or any analysis software.

The controller can be positioned beside the vessel or mounted on a separate stand, depending on bench space. The vessel sits on a base plate with integrated heating or jacketed connections. Four peristaltic pumps are mounted on the controller or on a separate pump head stand.

The system runs on standard laboratory power. No compressed air is required if you use the internal air pump (check specifications with supplier). The optional mass flowmeter requires a regulated air supply at 1–2 bar.

Data management and compliance features

The Siemens PLC control system records data continuously. The following functions are included:

  • Real‑time display of all process variables on the 10‑inch screen

  • Data recording at user‑selectable intervals

  • Data analysis functions (trends, minimum/maximum, integrated values)

  • Output printing to a connected printer or PDF file

  • Password management with multiple user levels

  • Abnormal analysis: the system flags events such as sensor drift, pump failure, or communication errors

  • Over‑limit alarm: audible and visual alerts when any parameter exceeds set safety limits

These features meet the documentation requirements for most non‑clinical research applications. For GMP environments, contact the supplier for validation documentation.

Ordering and delivery information

Model MSINOBIO‑JGSWISS ships as a complete system including:

  • Glass vessel (user‑specified volume, 0.2–50 L)

  • Vessel headplate with ports for sensors, feeding, and gassing

  • Stirring system (mechanical or magnetic, user‑specified)

  • Four peristaltic pumps installed

  • 10‑inch touch screen controller with Siemens PLC

  • USB data export cable

  • Power cord

  • User manual and quick start guide

The customer must specify the following when ordering:

  1. Vessel volume (litres)

  2. Vessel type (single‑wall electric heating, or double‑wall jacketed)

  3. Stirring mode (mechanical standard, or magnetic optional)

  4. Gas control type (rotor flowmeter standard, or mass flowmeter optional)

  5. Whether the external chiller is required

Optional accessories can be ordered separately:

  • Replacement stirring paddles (different types)

  • Additional peristaltic pump heads

  • External chiller unit

  • Mass flowmeter upgrade

  • Multiple air intake manifold

Request a quotation or technical consultation

For pricing, lead time, or a live online demonstration of the benchtop microbial bioreactor, contact us. Specify your required vessel volume and any optional features when requesting a quote. Volume discounts may apply for multiple units or for complete laboratory setups including multiple bioreactors and a central control station.

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